How to onboard to Level 2 using the VP-API Specification

Setting up Level 2 involves seamlessly integrating resources with the EJP RD VP API Specification. This is facilitated by installing any one of a suite of optional tools. Specifically, we offer five solutions for Level 2 onboarding, which are described in the following sections. Figure 7 depicts the steps of the Level 2 onboarding process.

Level 2 onboarding process overview

Figure 7 – Level 2 onboarding process overview

Level 2 onboarding solutions

Overview of the Level 2 onboarding solutions

Solution

Description

Capabilities

Licensing

Support Offered

Supports Level 1?

Supports Level 2?

RD-Nexus

RD-Nexus is a dedicated data discovery tool that adapts to many use cases and diverse datatypes. It utilises conventional and graph-based technologies to leverage semantic similarity and ontology mapping standards and is compatible with any input data format. Compliant with all major RD standards.

Support for Any/All EJP RD Beacon v2 queries; Storage and Query of Metadata; Storage and Query of safe (or rich) demographic, sample, phenotypic and other data (omics, tabular, images); Ingest/Use any data format; Real-time query execution; Powerful similarity searching (phenotypes and disease); Enforce ontologies or controlled vocabularies; Dockerised & Non-Dockerised Install options; Inbuilt modular query & admin interfaces; Supports federated AuthN/AuthZ (inc LS AAI); Secure operation across firewall (via polling); Create/Manage secure custom networks.

RD-Nexus is free to use under the MIT License.

Yes: Local installation and hosting options available. Demo and customisation support. Guidance on setting up private networks.

Yes

Yes

MOLGENIS

MOLGENIS (MOLecular GENetics Information Systems), is an open-source platform designed for managing and analyzing complex biomedical and genetic data. It supports the creation of RD registries, including discovery functions.

Supports EJP RD Beacon v2 queries; Structured Data Management; FAIR data sharing; secure access; Scripting & visualisation; Harmonization and integration; Task automation; High-performance computing.

MOLGENIS is free to use under LGPLv3 License.

Yes. Helpdesk available for any developer or user questions. Additional services offered for hosted installations and backups at a low fee.

Yes

Yes

Beacon-in-a-Box

Specialised version of the GA4GH Beacon adapted to enable easy setup of EJP-RD Level-2 services.

Beacon deployment for /catalogs & /individuals endpoint; Docker & Docker-less deployment.

Beacon is free to use under the Apache License 2.0.

Yes

No

No

FAIR-in-a-Box

FAIR-in-a-Box software enables the setup of a local Fair Data Point that holds your data in an accessible triple-store, with EJP RD Beacon v2 services.

Supports EJP RD Beacon v2 queries for both the /catalogs & /individuals endpoints; Dockerized installation.

FAIR-in-a-box is free to use; individual components have distinct licenses selected by their (third-party) authors.

Yes

Yes

Yes

EJP RD Beacon v2 DIY

A custom solution can be created by any developer comfortable with Python/Flask or similar backend technologies (support and guidance on this is available).

Licensing will depend on the technologies chosen for your custom solution.

No

Beacon4Biobanks

A solution specific for biobanks that are part or plan to be part of the BBMRI Sample Locator.

Beacon4Biobanks implements the /individuals and /biosamples endpoints of the VP API Specs by querying the FHIR Store of the Sample Locator

It is based on the Beacon Reference Implementation so it has the same license (Apache License 2)

No

Yes